Category Archives: Metagenomics

Incorporating 16S Gene Copy Number Information Improves Estimates of Microbial Diversity and Abundance

Kembel SW, Wu M, Eisen JA, Green JL (2012) Incorporating 16S Gene Copy Number Information Improves Estimates of Microbial Diversity and Abundance. PLoS Comput Biol 8(10): e1002743. doi:10.1371/journal.pcbi.1002743 The abundance of different SSU rRNA (ā€œ16Sā€) gene sequences in environmental samples … Continue reading

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High-Throughput Characterization and Comparison of Microbial Communities

Halwachs et al. 2012 Computational Medicine The human microbiome plays an important role in health and disease, but the structure of the bacterial communities and their interaction with the human body are still poorly understood. The recent introduction of next-generation … Continue reading

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Context matters ā€” the complex interplay between resistome genotypes and resistance phenotypes

Hi again, Here’s an interesting review on the importance of context with respect to antibiotic resistance genes and resistance phenotypes. Abstract: Application of metagenomic functional selections to study antibiotic resistance genes is revealing a highly diverse and complex network of … Continue reading

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Determination of Whether Quorum Quenching Is a Common Activity in Marine Bacteria by Analysis of Cultivable Bacteria and Metagenomic Sequences

I thought that some of you might be interested in this article. It’s interesting and there are a lot of seemingly good references and technical information. Abstract: The abundance of quorum quenching (QQ) activity was evaluated in cultivable bacteria obtained … Continue reading

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