Author Archives: cnfische

Cheese Rind Communities Provide Tractable Systems for In Situ and In Vitro Studies of Microbial Diversity

Culture independent to culture dependent analyses of cheese rind microbial communities. Top link is to the article. Bottom link is to a page where, if you scroll down, you will find a video blurb from the last author describing some … Continue reading

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CDC Threat Report 2013

Recent report by the CDC about antibiotic resistance. I thought it might be useful in introductions of some presentations. http://www.cdc.gov/drugresistance/threat-report-2013/

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A bacterial symbiont is converted from an inedible producer of beneficial molecules into food by a single mutation in the gacA gene

How little between happy coexistence and one-sided dominance… Stable multipartite mutualistic associations require that all partners benefit. We show that a single mutational step is sufficient to turn a symbiotic bacterium from an inedible but host-beneficial secondary metabolite producer into … Continue reading

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Bacterial-Derived Uracil as a Modulator of Mucosal Immunity and Gut-Microbe Homeostasis in Drosophila

http://www.sciencedirect.com/science/article/pii/S0092867413004509  All metazoan guts are subjected to immunologically unique conditions in which an efficient antimicrobial system operates to eliminate pathogens while tolerating symbiotic commensal microbiota. However, the molecular mechanisms controlling this process are only partially understood. Here, we show that … Continue reading

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Metformin Retards Aging in C. elegans by Altering Microbial Folate and Methionine Metabolism

Paper about how metformin, a drug used for diabetes, impacts c elegans longevity via its influence on the ‘gut microbiota’ (E. coli) http://download.cell.com/pdf/PIIS0092867413002675.pdf?intermediate=true

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Gene transfer from bacteria and archaea facilitated evolution of an extremophilic eukaryote

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Killing by bactericidal antibiotics does not depend on ROS

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