Interesting paper using AI-2 to modify gut microbiota composition.
- Streptomycin almost clears Firmicutes as Bacteroidetes dominate the gut microbiota
- Engineered Escherichia coli manipulate AI-2 levels in the mouse gut
- AI-2 produced by E. coli favors the Firmicutes while hindering the Bacteroidetes
- AI-2 can shape the microbiota composition under conditions of dysbiosis