Blaser paper – Missing microbes and obesity

Altering the Intestinal Microbiota during a Critical Developmental Window Has Lasting Metabolic Consequences

http://www.cell.com/cell/abstract/S0092-8674(14)00821-6

Highlights

  • Early life is a critical window of host-microbe metabolic interaction
  • Low-dose penicillin treatment amplifies diet-induced obesity
  • A transient early microbiota perturbation leads to long-term increased adiposity
  • The penicillin-altered microbiota has a causal role in inducing metabolic changes

Nice blog write-up from Ed Yong-  http://phenomena.nationalgeographic.com/2014/08/14/early-antibiotics-change-gut-microbes-fuel-obesity/

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