Monthly Archives: December 2013

Identification of T6SS-dependent effector and immunity proteins by Tn-seq in Vibrio cholerae

Jessica brought this paper to my attention before she left; it’s a new one in PNAS from the Mekalanos lab.  They use Tn-seq to identify new effector proteins associated with the Type VI section system in Vibrio cholerae.  It’s a … Continue reading

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Mammalian cells can express the gene encoding E. coli Shiga toxin

This is a really interesting and thought-provoking article in mBio.  The authors found that if they injected a high concentration of plasmid containing the gene encoding Shiga toxin (with native bacterial promoter), they saw that Shiga toxin was expressed and … Continue reading

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Drosophila substrate choice and progeny protection

Two recent papers on selection of substrates by Drosophila- Olfactory Preference for Egg Laying on Citrus Substrates in Drosophila. http://www.cell.com/current-biology/abstract/S0960-9822(13)01322-5   Competing dopamine neurons drive oviposition choice for ethanol in Drosophila http://www.pnas.org/content/early/2013/12/03/1320208110.abstract

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Bacterium can reverse autism-like behaviour in mice

Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders http://www.sciencedirect.com/science/article/pii/S0092867413014736 and some nice commentaries… http://www.nature.com/news/bacterium-can-reverse-autism-like-behaviour-in-mice-1.14308 http://sfari.org/news-and-opinion/news/2013/friendly-bacteria-treat-autism-like-symptoms-in-mice  

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