Monthly Archives: June 2013

Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

New Nature article out that identifies a link between secondary metabolites produced by the obese gut microbiome and liver cancer. Abstract: Obesity has become more prevalent in most developed countries over the past few decades, and is increasingly recognized as … Continue reading

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Gut metagenome in European women with normal, impaired and diabetic glucose control

Type 2 diabetes (T2D) is a result of complex gene–environment interactions, and several risk factors have been identified, including age, family history, diet, sedentary lifestyle and obesity. Statistical models that combine known risk factors for T2D can partly identify individuals … Continue reading

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Two words: magnetotactic bacteria

Optical magnetic imaging of living cells Magnetic imaging is a powerful tool for probing biological and physical systems. However, existing techniques either have poor spatial resolution compared to optical microscopy and are hence not generally applicable to imaging of sub-cellular … Continue reading

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A metabolomic view of how the human gut microbiota impacts the host metabolome using humanized and gnotobiotic mice

Abstract: Defining the functional status of host-associated microbial ecosystems has proven challenging owing to the vast number of predicted genes within the microbiome and relatively poor understanding of community dynamics and community–host interaction. Metabolomic approaches, in which a large number of small molecule … Continue reading

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Drosophila Host Model Reveals New Enterococcus faecalis Quorum-Sensing Associated Virulence Factors

Abstract: Enterococcus faecalis V583 is a vancomycin-resistant clinical isolate which belongs to the hospital-adapted clade, CC2. This strain harbours several factors that have been associated with virulence, including the fsr quorum-sensing regulatory system that is known to control the expression of GelE … Continue reading

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