Monthly Archives: May 2013

The gut microbiota of insects

link Abstract Insect guts present distinctive environments for microbial colonization, and bacteria in the gut potentially provide many beneficial services to their hosts. Insects display a wide range in degree of dependence on gut bacteria for basic functions. Most insect … Continue reading

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Dietary choice affects Shiga toxin-producing Escherichia coli (STEC) O157:H7 colonization and disease Another interesting link between members of the gut microbiota and butyrate, although unlike the last paper we discussed at journal club, this paper describes a negative effect of … Continue reading

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Topographic diversity of fungal and bacterial communities in human skin

  Abstract: Traditional culture-based methods have incompletely defined the microbial landscape of common recalcitrant human fungal skin diseases, including athlete’s foot and toenail infections. Skin protects humans from invasion by pathogenic microorganisms and provides a home for diverse commensal microbiota1. … Continue reading

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Bacterial-Derived Uracil as a Modulator of Mucosal Immunity and Gut-Microbe Homeostasis in Drosophila  All metazoan guts are subjected to immunologically unique conditions in which an efficient antimicrobial system operates to eliminate pathogens while tolerating symbiotic commensal microbiota. However, the molecular mechanisms controlling this process are only partially understood. Here, we show that … Continue reading

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Understanding microbial cooperation

James A. Damore, Jeff Gore Journal of Theoretical Biology The field of microbial cooperation has grown enormously over the last decade, leading to improved experimental techniques and a growing awareness of collective behavior in microbes. Unfortunately, many of our theoretical … Continue reading

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Bacterium Induces Cryptic Meroterpenoid Pathway in the Pathogenic Fungus Aspergillus fumigatus

Neato! Abstract: Stimulating encounter: The intimate, physical interaction between the soil-derived bacteriumStreptomyces rapamycinicus and the human pathogenic fungus Aspergillus fumigatus led to the activation of an otherwise silent polyketide synthase (PKS) gene cluster coding for an unusual prenylated polyphenol (fumicycline A). The meroterpenoid … Continue reading

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Transcriptome of the Lymantria dispar (Gypsy Moth) Larval Midgut in Response to Infection by Bacillus thuringiensis

Abstract: Transcriptomic profiles of the serious lepidopteran insect pest Lymantria dispar (gypsy moth) were characterized in the larval midgut in response to infection by Bacillus thuringiensis kurstaki, a biopesticide commonly used for its control. RNA-Seq approaches were used to define … Continue reading

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