Monthly Archives: April 2013

A metagenome-wide association study of gut microbiota in type 2 diabetes

Hi JoLab, Jo suggested that we discuss this paper for our next journal club. Essentially, this group has developed a MGWAS (metagenome-wide association study) and identified microbial markers of type II diabetes. http://www.nature.com/nature/journal/v490/n7418/full/nature11450.html Advertisements

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Microanatomy at Cellular Resolution and Spatial Order of Physiological Differentiation in a Bacterial Biofilm

This paper will likely be most interesting to the microbial communities folks.  It has some beautiful images showing differentiation within E. coli biofilms, demonstrating how at different depths, bacteria have unique morphological characteristics and produce different extracellular factors (flagella, curli) … Continue reading

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Comparison of the Compositions of the Stool Microbiotas of Infants Fed Goat Milk Formula, Cow Milk-Based Formula, or Breast Milk

Abstract: The aim of the study was to compare the compositions of the fecal microbiotas of infants fed goat milk formula to those of infants fed cow milk formula or breast milk as the gold standard. Pyrosequencing of 16S rRNA gene … Continue reading

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Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis Hi Lab, Nature Medicine has the coolest stuff!  This paper was written up by Gina Kolata in Sunday’s New York Times.  Koeth et al from the Cleveland Clinic … Continue reading

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Microbiology: The life beneath our feet

Jansson and Prosser Nature 494:40-41 Our planet’s soils teem with microorganisms that regulate processes from crop productivity to carbon sequestration. Molecular analysis contributes hugely to the characterization of microbial communities, but how can we better understand their ecological functions? Two … Continue reading

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Sex Differences in the Gut Microbiome Drive Hormone-Dependent Regulation of Autoimmunity Hi Lab, This is the paper I mentioned in Journal Club.  They use non-obese diabetic (type 1 diabetes) mice to show that the elevated levels of testosterone, caused by … Continue reading

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