Monthly Archives: October 2012

Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour

This review appears in Nature Reviews Neuroscience and explores the experimental evidence for a “microbiota–gut–brain axis” that may modulate brain function and behavior. Though personally I’m not convinced there’s anything more in the data presented here than associations (rather than … Continue reading

Posted in Metabolism, Microbial communication, Microbial Communities, Microbiome, Symbiosis | 1 Comment

Infection-Induced Host Translational Blockage Inhibits Immune Responses and Epithelial Renewal in the Drosophila Gut

Forgive me if someone has already posted this. This is an interesting article from Lemaitre lab, published in July in Cell Host and Microbe. Chakrabarti and colleagues show that the fly pathogen Pseudomonas entomophila “induces irreversible damage to the Drosophila … Continue reading

Posted in Drosophila, Infection and Pathogenesis | Leave a comment

A metagenome-wide association study of gut microbiota in type 2 diabetes

Metagenome_Diabetes Assessment and characterization of gut microbiota has become a major research area in human disease, including type 2 diabetes, the most prevalent endocrine disease worldwide. To carry out analysis on gut microbial content in patients with type 2 diabetes, we developed … Continue reading

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Computational design of genomic transcriptional networks with adaptation to varying environments

Carrera, J., Elena, S.F. and Jaramillo, A. (2012). Computational design of genomic transcriptional networks with adaptation to varying environments. Proc. Natl. Acad. Sci. USA 109: 15277-15282. Link to article Transcriptional profiling has been widely used as a tool for unveiling … Continue reading

Posted in Microbial evolution, Network Analysis | Tagged | Leave a comment